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Exposure definitions are in need of improvement in order to focus on primary insufficient milk supply.
In a case-control study of women with breast cancer, it is unlikely that many of these women would have experienced primary insufficient milk supply due to its low incidence rate, requiring a large sample size.
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However, data from randomized controlled trials suffer from concerns about overreliance on secondary rather than primary prevention, insufficient intervention and follow-up periods, particularly regarding the incidence of cancer, inappropriate supplement doses, and unsuitable cohorts for testing the hypothesis.
The observed underuse of mammography is mostly related to clinical and medical factors such as advanced patient age, comorbidities, late disease stage of primary cancer, insufficient teamwork between oncology specialists and primary care physicians [ 67, 68], and inadequate instructions on preventive care.
Insufficient mammary glandular tissue, a primary cause of insufficient milk supply, is a rare phenomenon.
Freedom of information responses from 131 local authorities showed that 32 – a quarter of the total – believe that government funding for additional primary places is insufficient to meet demand for 2015/16, and 33 thought Department for Education (DfE) cost assumptions for new places were not realistic.
An overly large cup and insufficient primary and secondary fixation can be implicated.
Pre- and in-service teacher education did not provide much content knowledge about science, which explains why primary teachers have insufficient content knowledge about science.
There is insufficient primary empirical evidence to draw broad conclusions regarding best practice for breast cancer follow-up care in terms of (a) patient involvement in care, (b) reductions in morbidity, and (c) cost effectiveness of service provision.
Animals were excluded if they encountered at least one of the following exclusion criteria: unusual suffering, loss of weight exceeding 20% of initial measurement and insufficient primary lesion leading to a non-complete paraplegia before grafting.
Seven patients were excluded due to insufficient primary tumor tissue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com