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"primary indication" is correct and usable in written English.
You can use the phrase to refer to something that serves as the first or closest indication of something. For example, "The primary indication of her unhappiness was her sudden withdrawal from social activities."
Exact(60)
Uterine leiomyomata (UL) are a major source of gynecologic morbidity and the primary indication for hysterectomy.
Its primary indication of the passage of time is that Ms. Ryan's blond hair keeps getting shorter.
The primary indication for the use of antipsychotics is schizophrenia, erroneously called split personality.
Subjects had predominantly been implanted for MDD, but 2/14 had a primary indication of OCD with comorbid MDD.
Slug tests yielded primary indication to the low permeability of the OSU despite its high porosity (30 40%).
Implant loosening – commonly linked with elevated initial micromotion – is the primary indication for total ankle replacement (TAR) revision.
The primary indication for polyols has been in the production of foods for people suffering from diabetes because unlike sugars, polyols are not readily absorbed in the intestine.
While the primary indication for EEG monitoring was to evaluate for seizures as the cause of AMS, only 8% of cEEGs and 1% of sEEGs revealed seizures.
The primary indication for the use of antipsychotics is schizophrenia, a severe mental disorder characterized by delusions, hallucinations, and sometimes unusual behaviour.
Uterine leiomyomata (UL) are the primary indication for hysterectomy and are 2 3 times more common in black than white women.
As a result of the Early Treatment for ROP (ETROP) randomized trial, the presence of plus disease is now the primary indication for laser treatment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com