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T. pallidum is a primary human pathogen that has eluded in vitro cultivation (10 ).
This report is the first to document introduction of a primary human pathogen into free-ranging wildlife.
This report, however, represents the first clearly documented case of a primary human pathogen infecting free-ranging wildlife.
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Enterobacter species causes opportunistic infections, and could be primary human pathogens [ 4].
Here we sought to use microarray technology to decipher simultaneously transcriptional changes in a human pathogen of primary public health importance, Mycobacterium tuberculosis, and in its main host cells, macrophages (Mφs) and dendritic cells (DCs) throughout infection.
Such an analysis compared the primary transcriptomes of the major human pathogen Helicobacter pylori under mid-logarithmic growth phase versus acid stress conditions, mimicking the host environment.
Initial screening identified a secreted activity by pathogen-activated primary human and mouse B lymphocytes, and by many types of neoplastic B cells spontaneously.
Although approximately 30 species have been recognized so far, Naegleria fowleri is the only human pathogen that causes primary amoebic meningoencephalitis (PAM) [ 2].
In the present study, we focused on the response of CD4+ T cells to primary acute infection with a common human pathogen.
Burkholderia mallei (Bm), the causative agent of the predominately equine disease glanders, is a genetically uniform species that is very closely related to the much more diverse species Burkholderia pseudomallei (Bp), an opportunistic human pathogen and the primary cause of melioidosis.
Next, we assessed whether the use of PC from host cell also occurs during pre-erythrocytic development of the human pathogen P. falciparum in micropatterned human primary hepatocytes (March et al., 2013).
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