For Hausman, the primary hallmark of transsexuality is the sheer demand for transsexual surgeries through which transsexual subjects are constituted as such (1995, 110).
Progressive asymmetric degeneration of nigrostriatal dopaminergic innervation is a primary hallmark of Parkinson's disease.
Moreover, in Western blot analyses, H3.7 did not react with anti-H3K27me3 pAbs, the primary hallmark for heterochromatic blocks.
Rapid and uncontrolled proliferation is the primary hallmark of cancer and underlies various other characteristics of tumours, e.g. angiogenesis and altered metabolic profiles [ 34].
ALS is a fatal, neurodegenerative disease in which the primary hallmark is the selective degeneration of upper motor neurons and lower spinal motor neurons.
This is of considerable importance as the primary hallmark of sickle cell disease is the ability of RBCs to abnormally interact with endothelial cells, leukocytes and platelets, and these cell-cell interactions are mediated through activation of RBC surface adhesion receptors.
This abnormal tau, a transport protein, is one of the primary pathohistologicall hallmarks of AD, and is the cause of neurofibrillary tangles in humans [ 101].
Along with NFTs, Aβ plaques are considered a primary pathological hallmark of AD and Aβ load is often used as a marker of AD severity [ 1, 35].
