Sentence examples for primary fate of from inspiring English sources

The primary fate of pyruvate in the liver is carboxylation to form oxaloacetate, which is in rapid equilibrium with malate and fumarate.

Oxidation occurs predominantly in the liver to a ferric-oxide (Fe-O) intermediate, the primary fate of which is thought to be trichloroacetyl chloride (TCAC), which then hydrolyses to yield trichloroacetic acid (TCA).

Although the primary fate of endocannabinoids is inactivation through hydrolysis, increasing evidence indicates that these compounds are also subject to most of the oxidative metabolic pathways that lead to eicosanoid biosynthesis.

In Drosophila, while imaginal discs can retain their primary fate during extended periods of in vivo culture, a few examples were observed in which the cells would adjust to another disc fate, a process termed transdetermination [32].

Indeed, complete command of this primary fate choice may even be incompatible with the underlying nature of the pluripotent ground state (see below).

Progenitor cells can be reversibly transformed into stable-bleb cells irrespective of their primary fate and motile characteristics by increasing myosin II activity through biochemical or mechanical stimuli.

Using tools from robust control theory, we show that the limitations of renewal control can be circumvented through the introduction of lineage branching, with feedback promoting alternate fate choice at the expense of both primary fate choice and self-renewal.

And when the purpose of an alternative fate is solely to control the numbers of cells that adopt a primary fate (that is, when the alternative fate is death or emigration), fate control is associated with the extra 'overhead' (in terms of time and materials) of producing cells that are not actually needed.

By contrast, a fate control strategy is minimum phase, because differentiation (down a primary fate pathway) and renewal can be suppressed simultaneously (through up-regulation of progression toward an alternative fate).

This is in agreement with previous studies, showing that the primary metabolic fate of exogenous lactate uptake was subsequent oxidation [30].

By John Cassidy March 27 , 2016After decisive victories in the Alaska, Hawaii, and Washington Democratic primaries, the fate of Bernie Sanders's campaign for President is still unclear.