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Among them, caspase-3 is a primary executioner of apoptosis induced by a variety of stimuli including H2O2 [31], [31].
Caspase-3, a primary executioner of apoptosis, was not activated in TAP-Lxn cells but its active form was detected in control cells from 24 h post irradiation.
In accordance with previous studies, caspase-3 was the primary executioner of caspases activated during goniothalamin-induced apoptosis [ 17, 18, 25].
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Caspase-3 belonging to a family of cysteine proteases is main executioner of apoptotic cascade pathway.
Caspase-3 is the main executioner downstream caspase-9.
In 1994 I attended a meeting at the Smithsonian Institution in Washington, DC and sat across the table from former Defense Secretary Robert McNamara, one of the primary architects and executioners of the Vietnam War.
Sri Lanka's chief censor is an amiable executioner of words.
The combination also induced activation of initiator caspases-2, -8 and -9 and the executioner caspase-3 in cell lines and primary CLL cells, suggesting that both the intrinsic and extrinsic apoptotic pathways are activated.
Caspases-3 and -7 are executioner Caspases and so their levels report directly on apoptosis, instead of cell death in general (as in the primary assay).
An executioner.
His executioner?
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