Sentence examples for primary elimination from inspiring English sources

31 The primary elimination route of sitagliptin is via active tubular secretion in the kidneys (~79%) and the terminal half-life is 8 12 hours.

Isolates from all phases of the adaptation process were screened in PSGHL as the primary elimination point for those cultures not able to ferment xylose well.

The alkyl halide must be unhindered (usually primary), or elimination will compete with the desired substitution.

The higher clearance in pregnant women (FPREGCL = 1.14) is due to a higher than proportional increase in glucuronidation, a proportional increase in oxidation and a subproportional increase in primary renal elimination [ 11].

The primary metabolic elimination found for BMS-911543 in liver microsomes and in bile-duct cannulated rats was mainly attributed to the metabolism by cytochrome P450 (CYP) 1A2, which mediated the formation of metabolite M1 (see Supplementary Figure S1 for structure).

If the primary route of elimination for Hg were through RBC turnover, we would expect the elimination curve to have more closely followed the zero-order elimination curves shown in Figure 3.

The legal enunciation of rules of criminal law (mostly "prohibitions") has as its primary goal the elimination or at least discouraging of the specified kinds of action (or omission).

In renal diseases, the pharmacokinetics of many drugs are altered even when the primary route of elimination is not renal, due to changes in protein binding, volume of distribution, and/or acid-base disturbance [17].

The primary endpoint was elimination of daily troublesome regurgitation or atypical symptoms.

These agents were considered because of the known differences in their primary pathways of elimination.

The polymer drug linkage must be completely stable in transit, not degrading too rapidly in the bloodstream or during renal excretion the primary route of elimination.