Sentence examples for primary effectors of from inspiring English sources

We have studied the primary effectors of endogenous microrevascularization, endothelial progenitor stem cells (EPC) and their potent chemokine stromal cell derived factor 1-alpha (SDF).

These encouraging results suggest a potential role for neurons as primary effectors of cytokine activity in mediating behavioral responses to immune challenge.

Despite the efforts to elucidate the effects of such antibodies on neurons, only a few onconeuronal antibodies have been identified as primary effectors of neurological symptoms.

While modulation of TCF/LEF-1 activity by LRP6-ICD or AES was significant, the scale of modulation in relation to overexpression clearly indicates that both proteins act as modulators and not primary effectors of Wnt pathway transcriptional activity.

CD8+ T cells have been shown to be the primary effectors of ECM [22], whereas NK and CD4+ T cells have been implicated in the induction phase of ECM [22], [23].

CD8+ T cells were recently shown to be the primary effectors of CM in the Plasmodium berghei ANKA mouse model, although their precise mechanism of action remains unresolved [37].

The primary effector of the RAS is the octapeptide angiotensin (Ang) II, a potent regulator of blood pressure and water homeostasis.

This has shifted attention to the primary effector of the fibroproliferative response, the fibroblast itself.

The phagocytic oxidative burst is a primary effector of innate immunity that protects against bacterial infection.

PKA is the primary effector of the cAMP signal, and consists of two catalytic subunits (PKA-C) bound non-covalently to a dimer of regulatory subunits (PKA-R).

Our data further emphasizes the importance of reduced SERCA as a primary effector of cardiac contractility, and therefore a worthy target for such strategies.