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"I think that the primary downside would be that to the extent the economy softens and the rest of the industry lowers its ticket prices, we could see a company with a thin operating margin that would be unable to support itself like other larger, more established companies".
The primary downside of vaccine vials containing a higher number of doses is the increased chance that unused doses will go to waste.
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One of the primary downsides, though, is hearing those culture-defining songs I get stuck playing over and over again until I want to go all Van Gogh on both of my ears.
Anthony D. Weiner, lagging in the Democratic primary polls, apparently saw little downside in overpromising.
On the downside, the phone's primary microphone is located on the bottom of the device, to the left.
There is merit to this suggestion, but the downside is that it may not improve primary tissue processing expertise, and may neglect local capacity building and sustainability.
Concomitant improvements in communications technology, process and protocol in primary and community care are urgently required to offset a potentially serious downside to patient safety.
Like most of the TV chefs I've interviewed, one big downside to television fame are some assumptions people make about their primary work, as chefs and restaurateurs.
On the downside, you're sleeping only feet away from one of the Taliban's primary targets.
There is also however, a downside to our increasing predisposition to rely on this and other electronic media as our primary forms of communication.
No downside?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com