Among trafficking-associated proteins, the Rab family expanded most in evolution, suggesting that it provided the primary diversification element in the evolution of trafficking [ 10].
Much research into this time period has focused on the ventilation of the oceans, as this is widely considered a primary factor driving the diversification of complex, multicellular life.
The geological events appear to have played a primary role in the diversification of Chinese Glyptosternoids.
At evolutionary timescales, colonization of novel animal hosts may lead to speciation and thus constitutes a primary process driving the diversification of symbiotic animals [ 6- 8].
By extending our domain search to include entire proteomes, we find evidence for a complex intersection of domain shuffling, gene duplication, and de novo domain evolution as the primary mechanisms for the diversification of the KLF/SP gene family across the Metazoa.
Key features of this process in the last 6 8 years have been decentralisation of HIV treatment and care to primary health facilities and diversification of HBC programmes to provide psycho-social support in various ways to those infected and affected by HIV and AIDS.
Given the phylogenetic origin of the E spl -complex dE spl -complex this studemonstratedole of these genes in bristhisformation, it istudypting to speculand thet selection proleures related toftheseensory input provided by macrochaetes was a primary factor drivingenes dinersification of genes in this complex.
Other recent studies on myeloproliferative disorders and melanoma, kidney and pancreas tumors or, again, in breast cancer, arrived at similar conclusions, pointing to a late, metastasis-specific diversification of primary tumor-derived cells (see Wu et al., Figure S14, and Clifford ).
The first unequivocal movements out of Australasia were reconstructed to have occurred after the origin and early diversification of the primary campanulid clades.
Indeed, with the on-going reform, development and diversification of the primary health care sector (especially in Australia) we believe there may be new scope for caseload-specific classification and assessment of services performed by primary health care professionals in general, be they delivered via the traditional GP consultation format or otherwise.
