Sentence examples for primary disruption of from inspiring English sources

With ischaemia bone necrosis occurs but in avn necrosis is due to primary disruption of the blood supply as opposed to a primary mechanical bone injury in stress fractures.

Excess/chronic glucocorticoid-induced insulin resistance could partially result from a primary disruption of lipid homeostasis.

This normalization allows us to estimate the effect of the stress on the primary disruption strain independently of the effect of the disruption itself.

Imbalances of lipid traffic or metabolic homeostasis may either contribute to or represent the primary disruption associated with the development of many lipid-related diseases [ 7].

This comparison is instructive because, in the absence of a primary disruption mutation, compensatory mutations are not available to the reference strain.

Disruption type did not explain any of the variation in growth rate amongst the 30 secondary mutation strains constructed from each primary disruption strain.

Bipolar disorder is characterised by a primary disruption in mood.

However primary sequence disruption of the site would influence both PuF (repressive) and SP1 (stimulatory) interaction very strongly.

In general, functional outcome following spinal cord injury will highly depend on the severity of both primary anatomical disruption of nerve tracts (due to contusion, laceration, penetration, etc).

Although RASSF9 null expression resulted in diminished filaggrin expression indicative of altered or delayed terminal differentiation in mouse primary keratinocytes, the disruption of a single allele (RASSF9+/−) was not sufficient to yield this characteristic (Figure S11).

In the mouse inner ear, there is a complex relationship between PCP, IFT and the position of the kinocilium (a specialized primary cilium), where disruption of ciliogenesis by conditional deletion of Ift88 reveals that this IFT protein is required to allow basal body migration in response to PCP signals [51].