Sentence examples for primary difficulties in from inspiring English sources

One of the primary difficulties in evaluating the effectiveness of lumbar fusion is that, with the exception of spondylolisthesis, specific diagnostic indications for surgery are poorly defined.

There is opulent literature suggesting that one of the primary difficulties in locating active transcriptional sites is due to the majority of the mammalian genome being transcribed and most regulatory sequences being multi-functional [1], [2], [3], [4].

One of the primary difficulties in attempting to initially identify volatile biomarkers from human patients is the vast variation that can be due to uncontrolled variables such as genetic and dietary differences, personal care product usage, and other environmental variables that can impact on body odor volatiles.

The use of detailed methods, such as those proposed by Beaton et al. [ 16], was important to identify the primary difficulties in the development of equivalent versions.

One of the primary difficulties in measuring acceptability is that the term is often inclusive of a number of different constructs including whether the patient is willing to implement changes to their behaviour [ 63].

One of the primary difficulties in species designation is that the process of speciation requires an extended period of time during which various attributes of species-level distinction are attained [ 2].

"The primary difficulty in staff planning at this time was the fact that neither the field nor Headquarters possessed detailed information on military figures in Iran.

But insiders say the primary difficulty in prosecuting Mr. Milosevic for Kosovo will be to establish the credible links between Mr. Milosevic and the looting, raping and killing attributed to the Yugoslav forces on their rampage through Kosovo.

A primary difficulty in using a data set of the distribution of volcanic vents is determination of independence of events.

The primary difficulty in applying the Poisson approximation is the determination of the optimal parameter μ n, which is higly dependent on the structure of the pattern Λ.

The primary difficulty in the identification of Hammerstein nonlinear systems (a static memoryless nonlinear system in series with a dynamic linear system) is that the output of the nonlinear system (input to the linear system) is unknown.