Sentence examples for primary defects in from inspiring English sources

As such, impaired skeletal muscle insulin action and glucose utilization are the primary defects in the development of type 2 diabetes (DeFronzo and Tripathy, 2009).

The placenta is fetal tissue and our results strengthen the argument that primary defects in the placenta play a central role in the development of preeclampsia.

Thus, peripheral T cell phenotypes were due to both primary defects in the thymic microenvironment and secondary conditions in the peripheral environment.

Adipose tissue dysfunction belongs to the primary defects in obesity and may link obesity to several health problems including increased risk of type 2 diabetes, fatty liver, and cardiovascular disease [1] [6].

In the first scenario, primary defects in the QC region are expected, while in the second scenario, a decrease in meristem size would be observed before QC and stem cell defects appear.

As embryos homozygous for the GPR126LacZ allele die before this time point it is difficult to distinguish primary defects in heart development from secondary effects of circulatory failure due to other reasons.

In contrast, the primary defect in SSS and the acromelic dysplasias is more likely to be defective cell-surface interactions with microfibrils rather than a defect in microfibril assembly or stability.

Accidental hypothermia concerns a body core temperature of less than 35 °C without a primary defect in the thermoregulatory system.

It appears that the primary defect in the disorder may have occurred in the embryological development of the lower leg [4, 6].

This suggests that a primary defect in CFTR expression is not the root cause of neutrophilic inflammation in these disease contexts.

The depressed palea1 (dp1) mutants show a primary defect in the main structure of palea, implying that palea is a fusion between the main structure and marginal tissues on both sides.