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Although the humoral immune response generates the primary correlate of protection from disease, robust T cell responses could enhance ZIKV vaccine efficacy.
Whilst the presence of PA specific toxin neutralizing antibodies is the primary correlate of protection in current human vaccines, reliance upon this antigen alone may limit the promotion of long-lasting memory.
While we have previously shown that rabbits immunized with plant-derived CRPV L1 protein were protected against live CRPV challenge in the absence of detectable neutralising antibodies [ 21], this is the only such result to our knowledge, and it is generally taken as given that the primary correlate of protection against papillomavirus infection is the presence of neutralising antibodies.
Although DENV NAbs are widely considered to be a potential primary correlate of protection against dengue disease, 7 no protective threshold titer similar to the minimum protective titer of 1 10 for Japanese encephalitis virus has yet been established for DENV.
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"The exciting thing in the lab is that we are showing physically tangible effects whose primary correlates are subjective," he said.
By using tephras as the primary correlating horizons, we are also able to correlate sediment color variations at shallow- and deep-water sites in the JS.
Although urban residence is consistently identified as one of the primary correlates of non-communicable disease (NCD) [ 1, 5, 6], the nature of the association remains poorly understood.
By including a 'global' measure of social support, specific sources of social support will not be identified, which can lead to misconceptions of the primary correlates and possibly biased results.
Increasing thickness of the cutaneous primary correlates with worsening survival outcomes, dropping from 96%10-year10-yearvalesionsesions <1 mm, to 54% for lesions >4 mm; even for lesions <1 mm in thickness, there is further deterioration in outcome between lesions <0.25 mm thickness and those >0.75 mm [75].
Although urban residence is consistently identified as one of the primary correlates of non-communicable disease in low- and middle-income countries, it is not clear why or how urban settings predispose individuals and populations to non-communicable disease (NCD), or how this relationship could be modified to slow the spread of NCD.
Loudness [16] is defined as quality of a sound which is a primary psychological correlate of physical strength (amplitude) which is measured in decibels (DB) [11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com