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No primary complex was detected.
No primary complex was detected (tr = 8 minutes) at any time of incubation.
According to Leung et al., our patient had a primary complex partial dislocation.
Conclusion: While secondary complex was detected inside and outside the cells, primary complex was absent in extracts and effluxes at any time of study.
According to our results, the activity detected in cell effluxes is related to the exit of secondary complex, rather than the exit of primary complex after reversibility of the original conversion inside the cell.
In this sense, it is postulated by some authors that the conversion to secondary complex is reversible, and over the time, a percentage of the primary complex tends to appear and elute from cells.
Similar(35)
Under these conditions, only partners directly associated in primary complexes co-precipitate with CD81.
Hence, it has been suggested that primary complexes constitute functional units.
Within this network of interactions, tetraspanins form primary complexes with a limited number of proteins termed tetraspanin partners.
In this report, we focus on the functional relevance of primary complexes formed by tetraspanins CD9 or CD81 with CD9P-1.
To confirm the importance of these primary complexes, the effect on cell motility of the chimera protein CD9×82 which does not associate with CD9P-1 [24] was investigated.
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