Exact(2)
In total, three primary comparisons between the treatment groups were defined and tested, namely (1) 75 mg Petasites extract versus placebo, (2) 50 mg Petasites extract versus placebo and (3) 75 versus 50 mg Petasites extract.
Primary comparisons between treatment groups were analyzed by using multiple regression with the factors treatment or portion (with amounts of 4, 2, 1, and zero portions), age (with levels of young, middle, and old), sex (men compared with women, if needed), study center, baseline BMI, and average compliance over the 12 mo.
Similar(58)
Participants: Post cardiopulmonary bypass patients for primary comparison between technologies (n = 20) and patients for comparison of variability within each technology (n = 20).
The primary comparison between groups was by covariate analysis of variance (ANCOVA), with baseline count as covariate.
The primary comparison between groups was the total AUC for the entire study (120 min); secondary comparisons were for the AUC between 0 min and 30 min, and between 30 min and 120 min.
Sample size was based on the primary comparison between the proportion of abatacept- and placebo-treated patients with RA at year 1, and was not computed with the intention of having adequate size to perform formal statistical tests.
The primary comparison between the 3 groups was a linear trend test based on linear regression for continuous endpoints, logistic regression for binary endpoints, and Cox regression for time-to-event endpoints.
Isoglycaemic hyperinsulinaemic clamps were used in the present study in order to observe the physiological mechanisms operating at ambient plasma glucose concentrations in the diabetic and control subjects, and in respect of the primary comparison between acipimox and placebo studies in the diabetic subjects, clamp glucose levels were similar.
For the primary comparison between booklet self management with telephone support and routine care, the point estimate for the absolute difference of 22.0%95%5% confidence interval 7.3%too 36.8%) indicated that five threee to 12) patients would need to be treated for one patient to report subjective improvement at one year.
Primary comparisons were between paracetamol plus ibuprofen and either drug alone, and secondary comparisons were between paracetamol and ibuprofen, using Dunnett's and Tukey's adjustments, respectively, for multiple comparisons.
Primary comparisons were between wait-list size categories.
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