Among 913 cases with documented primary clinical form, 744 (82%) were bubonic, 74 (8%) pneumonic, 87 (10%) septicemic, 6 (1%) pharyngeal, and 2 (<1%) gastrointestinal.
The clinical form of plague (e.g., bubonic, pneumonic, septicemic) was determined on the basis of explicit notations in the case records or from available clinical details; only the primary clinical form was considered.
A low number of individuals develop pneumonia, which is the main clinical form in immunocompetent patients (primary pulmonary histoplasmosis) with distinctive histopathological features, like chronic granulomatous infiltrate [ 69].
We developed a computer-based state-transition model that simulates the natural history of pneumonias (both primary endpoint pneumonia as defined by WHO [ 25, 26] and non-primary endpoint pneumonia) and serious clinical forms of pneumococcal diseases in order to evaluate the cost-effectiveness of routine vaccination with PCVs, compared to no vaccination from the societal perspective.
Human herpesvirus type 8 (HHV8) is the causal agent of all clinical forms of Kaposi sarcoma, of two B-cell tumors, namely, primary effusion lymphoma and multicentric Castleman disease, and the recently described HHV8 inflammatory cytokine syndrome [ 10– 10].
The activation of the primary somatosensory cortex observed in the present study is in line with several reports investigating experimental or clinical forms of allodynia [ 47, 48, 51– 51].
Four clinical forms are defined.
The model favors endometriosis as an outgrowth of primary cells different in their origin, canalization of pathological processes, manifestation diversity provoked by unique genetic background and epigenetic influences, which result in many different clinical forms of the disease.
There were two clinical forms of smallpox.
Most familial forms of CAA involve mutations within APP. [8] [14], and present with vascular deposition of Aβ causing a clinical phenotype akin to sporadic CAA, including either ICH or dementia as the primary clinical features.
