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Whether elevations in lactate after primary clearance (ie. secondary hyperlactataemia, SH) is associated with outcomes in critically ill patients remains unknown.
The primary clearance route for 64Cu-DOTA-knottin 3-4A is the kidneys, with probe uptake values ranging from ∼8 12%ID/g at 1−4 h post-injection, and decreasing to ∼2 4%ID/g at 24 h.
Surgical treatments have the highest primary clearance rates with initial cure rates up to 60 90%.
While vasculature-mediated internalization is thought to represent the primary clearance for VEGF in tissue [ 43], our model only implicitly represents such effects (through a clearance at z = -L), neglecting isoform-specific variation.
If the TP is a cytokine or modulates a cytokine which can effect regulation of various CYPs, and these CYPs provide the primary clearance pathway for the co-administered SMD, then a clinical DI study to examine potential interaction should be considered.
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To reduce the fault clearing time, this paper proposes two fast backup relaying algorithms which detect local and remote breaker failure before the expected primary fault clearance instant.
For opiates that have primary renal clearance, such as morphine and hydromorphone, decreases in GFR lead to more side effects (Davies et al 1996).
50 The primary metabolic clearance of dronedarone is driven by hepatic CYP3A4-dependent mechanisms, with a terminal half-life of approximately 24 hours.
Based on good correlation of failure load and damage distribution between experimental results and FE prediction, further investigation was extended to the effect of two primary assembly clearances on mechanical behavior of the π-joint.
Clearance of AK was evaluated at day 57 and included the primary endpoint, complete clearance of all visible lesions, and the secondary endpoints of partial clearance (defined as ≥75% reduction in lesion count compared with baseline) and percentage change from baseline in the total number of AKs.
The primary mechanism for clearance of micron-sized foreign bodies is phagocytosis by resident alveolar macrophages.
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