Sentence examples for primary cellular target from inspiring English sources

Importantly, the sensitivity of rabbit PMNs to the leukolytic activity of PVL mirrors that of human PMNs [17], making the rabbit an excellent model species because PMNs are a primary cellular target of PVL and the principal component of host innate immune defense.

Thus, the primary cellular target of Nrg1 is likely to be cardiomyocytes.

Surprisingly, genetic studies in Streptococcus pneumoniae found that topoisomerase IV, rather than gyrase, was the primary cellular target for ciprofloxacin.

The kinetics of action and primary cellular target(s) within the gonads are more easily determined using an in vitro approach, and they validate its use in addition to, or in place of, the classical in utero approach.

However, two inhibitors (ciprofloxacin and to a lesser extent 271327) have IC50 curves that closely match the IC50 curves for Mcm2-7 helicactivityvity, consistent with the possibility that the primary cellular target is Mcm2-7.

While the primary cellular target of BLV is B cells, recent studies suggest that monocytes, granulocytes, CD2+ T cells, CD3+ T cells, CD4+ T cells, CD8+ T cells and γ/δ T cells are also targets [ 4- 6, 20].

CD4+ T lymphocytes 89 and macrophages 90 are the primary cellular targets of HIV.

Inhibiting E6/E7 restores the functions of their primary cellular targets, p53 and Rb.

They generally occur in multiple diverse copies per cell (Table 2) and their primary cellular targets remain obscure.

O2– is a relatively unreactive radical and its primary cellular targets appear to be other radical species, such as nitric oxide (NO) or metals.

Our data provide a platform to evaluate molecular pathways or primary cellular targets of compounds for further development of antitumor agents.