Sentence examples for primary cell population from inspiring English sources

While it has been demonstrated previously that more differentiated cells demonstrate a lower reprogramming efficiency [11] and different somatic cell types possess differential reprogramming ability [12], [13], no study to date, to our knowledge, has identified subpopulations of cells within a primary cell population possessing differential reprogramming potential.

An alternative to generating immortalized lines of myogenic cells is the utilization of primary cell population enriched for myogenic precursors.

This did not occur in Adeno-Cre-infected cells from WT mice or in the fibroblast-like primary cell population from dio3fl/fl mice.

We recommend using a primary cell population that is abundant and easy to isolate using FACS, e.g., CD4+ T cells from mouse spleen or a passaged cell line.

Autogenous ("cell service," which consists of harvesting a primary cell population, cultivation, combination with an appropriate scaffold, and transfer to the clinic for use): "BioSeed-Oral Bone" (BioTissue Technologies, Germany) (2001) and "Osteotransplant DENT" (co.don, Germany) (2006).

As a hyaline cartilage, costal cartilage provides a differentiated, pure, primary cell population, circumventing the need for differentiation cues employed in conjunction with stem cells, and altogether avoiding associated ethical challenges.

Heterogeneity is a hallmark of cell biology, and is strongly evident in primary cell populations isolated from the same tissue [2].

Currently, we are routinely using primary cell populations to validate new questions and reagents that subsequently will be addressed in organ culture systems.

As culture conditions become better defined, either to support the specific expansion of homogeneous primary cell populations or to support the survival and expansion of complex primary cell mixtures derived from disrupted mucosal surfaces, so the utility of primary cell populations should increase.

The experiments with primary cell populations are at least one step further removed from reality than tissue pieces in organ culture but primary cells do provide biological value relative to standard immortalized epithelial cell lines.

This method allows for highly efficient transfection of DNA or siRNA into isolated primary cell populations or within mixed cell suspensions as well as into other cell populations that are considered difficult to transfect.