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We need to be able to identify it quickly and as accurately as possible and then, if they are its primary cause, to help family members prevent or stop its occurrence.
Oxidative stress is the primary cause to produce many long lived cytotoxic RCCs that form aggregates with proteins and lipids that generates advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs) which affect metabolic pathways (Ott et al., 2014; Semchyshyn, 2014).
Since promoter methylation is a primary cause to functionally inactivate tumour suppressor genes, DKK3 may act as a tumour suppressor in the human mammary gland.
However, the observation of a difference in differential activations between FM patients and health controls at very low force levels (0-1 Kg), but not higher force levels (2-4 Kg), supports that a generally higher maximal strength of controls compared with FM patients [ 24] is not the primary cause to the findings of this study.
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The causes of elevated CK and myoglobin levels in our study also were variable, but a primary cause seemed to be recent surgery (p < 0.001), especially prolonged surgery, in agreement with previous observations [23].
This study was designed to determine the temporal fluctuations in the primability of neutrophils in the preoperative, intraoperative, and postoperative periods of CPB, and specifically whether CPB was a primary cause leading to increased neutrophil priming and elastase release.
We suggest iron dyshomeostasis instead of a zinc defect is probably the primary cause contributing to SCD-EDS.
The causes of elevated CK and myoglobin levels in our study also were variable, but a primary cause seemed to be recent surgery (p < 0.001), especially prolonged surgery, in agreement with previous observations [ 23].
The primary cause is thought to be due to differences induced by sex hormones and their effects on gene expression as well as the immune system, but may also be due to innate physiological differences between males and females.
Each of these mechanisms has the potential to theoretically be the primary cause and lead to the other characteristics of T2DM (Fig. 1).
There are few clinic-based studies of PSH, and its real influence as a primary cause for referral to neurology outpatient offices is to be determined.
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CEO of Professional Science Editing for Scientists @ prosciediting.com