Sentence examples for primary biological function from inspiring English sources

Exact(19)

We performed functional enrichment analysis to identify the primary biological function (GO term) representing each of the groups.

If mutations that are neutral with respect to a protein's primary biological function cause substantial changes in promiscuous functions, these mutations could enable future functional evolution.

Bleomycin hydrolase (BLMH) is a neutral cysteine aminopeptidase that has been ascribed roles in many physiological and pathological processes, yet its primary biological function remains enigmatic.

Since a primary biological function of PPAR-γ is to serve as an intracellular sensor for changes in fatty acid or prostaglandin levels, its abundance and availability are important in determining the intensity of ligand responses.

Platelets rely on integrin αIIbβ3 (also known as glycoprotein GPIIb/IIIa) to perform their primary biological function, which is to help seal and repair the circulatory system after vascular injury [5].

In many cell types like muscle tissue, the activation of their primary biological function and energy demanding process drives mitochondrial metabolism via changes in redox, phosphorylation potential or Ca2+.

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Similar(41)

The mechanism of reversible phosphorylation executed through kinases and phosphatases is a mode of altering biochemical or structural properties of protein and is utilized for all primary biological functions.

The reason is that in addition to their primary biological functions, most proteins are at least modestly effective at performing a range of other "promiscuous" functions [ 1, 2, 7- 10].

This realization that demethylases potentially play widespread roles in protein demethylation raises an important question of whether the primary biological functions currently attributed to demethylases result from histone demethylation or other uncharacterized non-histone protein demethylase activities.

Scaffold choice, immunogenicity, degradation rate, toxicity of degradation products, host inflammatory responses, fibrous tissue formation due to scaffold degradation, and mechanical mismatches with the surrounding tissue are key issues that may affect the long-term behavior of the engineered tissue constructs and directly interfere with their primary biological functions [ 17].

Their primary biological role remains obscure; they perform a range of functions depending on the specific needs of the particular organism or tissue and its environmental circumstance.

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