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The primary analysis using WHO criteria had its basis in 7304 study participants.
We scanned the arrays using GenePix 4000B scanner (Axon Instruments/Molecular Devices, Sunnyvale, CA) and we performed the primary analysis using the GenePixPro 4.0 software (Axon Instruments/Molecular Devices) The primary analysis included spot finding, alignment and adjustment, fluorescence normalization, flagging out poorly hybridized spot, and background subtraction.
We also re-run our primary analysis using the same data as for the secondary analysis.
The primary analysis using ANCOVA will not adjust for any missing data.
Given the considerable number of patients with missing data, we repeated the primary analysis using multiple imputation by chained equations.
We performed sensitivity analyses by repeating the primary analysis using several different methods of reference creatinine assignment.
Similar(31)
Hence, our (limited) analysis using O*NET is based on a 2003 2010 CPS sample, whereas our primary analysis uses a larger CPS sample for 1998 2013.
The primary analysis used the Antiplatelet Trialists' Collaboration end points, which include: (1) cardiovascular, hemorrhagic, and unknown deaths, (2) nonfatal myocardial infarction, and (3) nonfatal stroke.
Our primary analysis used an ITT approach.
The primary analysis uses intent-to-treat methodology.
The primary analysis used all data in an intention-to-treat (ITT) analysis.
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