Sentence examples for primary alterations in from inspiring English sources

Conversely, primary alterations in adiponectin result in inverse correlation with TNF.

In the current study, compared with the healthy controls, the primary alterations in SCNs in patients with PI were the increased covariance between the sensory and motor regions.

In animal models of HCM, arrhythmias can develop before significant fibrosis occurs, suggesting that primary alterations in cardiomyocyte electrical properties, in addition to fibrotic scarring, underlie the arrhythmogenesis (Baudenbacher et al., 2008; Wolf et al., 2005).

Our findings reveal that some of the tested compounds, in particular TKI258, could provide therapeutic opportunity not only for patients with primary alterations in FGFR but also for acquired resistance due to the gatekeeper mutation.

Therefore, respiratory acid-base disorders are associated with primary changes in plasma bicarbonate concentration, while metabolic acid-base disorders are caused by primary alterations in other plasma ions, mainly chloride and sodium.

GP5d cells are MMR deficient because of primary alterations in MSH2 and MLH3, resulting in lack of MSH6 and MSH3 proteins as well (Cannavo et al, 2005; di Pietro et al, 2005).

Although it is not known if the reduction of endothelial progenitor cells represents a primary alteration in migraine or the consequence of migraine attacks, it might be possible that their alteration mediates the increased vascular risk.

But it is largely unknown whether this is due to primary alteration in BM progenitors themselves or their niches (endogenous microenvironment).

It is noteworthy that Met amplification in the form of extrachromosomal double minutes is also a primary alteration in the mutant Met knock-in mice that develop basal-like breast tumors [ 52].

These results suggest that lupus DCs do not have a primary alteration in their expression of CD40, but that the overexpression observed ex vivo may be the result of a chronic exposure or altered response to activators in vivo.

The in vivo findings in patients correlated with higher tension costs (ATP consumption per force development) measured in permeabilized muscle strips in vitro, indicating (i) that the defect in energetic efficiency of myofilament function is a primary alteration in sarcomere-positive HCM and (ii) can be faithfully analysed in vitro.