Sentence examples for primary active sites from inspiring English sources

In particular, it is demonstrated that mutual promotion between N and P doping induces ultrahigh ORR activity while N doping is identified as the primary active sites for the OER.

Brønsted acid sites generated in-situ with the assistance of water have been identified as the primary active sites for the dehydration pathway.

Notably, this assay measures only the activity of cystatin C at its primary active site, which interacts with papain-like cysteine proteases.

MnO2 was the primary active site for Hg0 catalytic oxidation.

The core sequence (His-Phe-Arg-Trp) is conserved in several species and is considered as the primary active site or 'message sequence'.

In this study, we examine the impact of drug-resistant mutations in HIV-1 protease on substrate recognition and demonstrate that most primary active site mutations do not extensively contact substrates, but are critical to inhibitor binding.

This is because this site is far from its primary active site which consists of the B-chain C-terminal α-helical region [ 2].

Among all NSAIDs, aspirin is a unique non-selective irreversible COX inhibitor due to its ability to acetylate the Ser530 hydroxyl group in the primary active site of COX-1 and COX-2 [ 31].

Biochemical and x-ray crystallography studies have defined 7 primary active site residues in M17 leucyl aminopeptidases involved in catalysis and binding of divalent cations, including a critical Zn2+ ion binding region [ 38, 39].

The compounds were found to be time-dependent inhibitors of HNE and were devoid of any inhibitory activity toward PR 3. The results suggest that highly selective inhibitors of serine proteases whose primary substrate specificity and active sites are similar can be identified by exploiting differences in their S′ subsites.

At least 3 distinct superfamilies of enzymes use the β-GF the primary scaffold for their active sites.