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In order to compare responses under different anaesthetics without the potential confound of activity measured outside of the primary activation region, we defined a rectangular (ROI) of about 11 mm that was restricted to the large bilateral contiguous activated area centred around the primary auditory region L2a.
The results showed that morphine administration produced significant changes in the spontaneous neuronal activity in more than one third of the total recorded neurons, with primary activation in the lateral pathway while both inhibition and activation in the medial pathway.
The results show that oxygen plays a dominating role in the primary activation of the alkanes by producing an HO2 and a hydrocarbon radical.
Primary activation of these nuclei exclusively in patients who experience nausea before the appearance of headache and trigeminal activation, demonstrates that nausea can be a centrally driven symptom in some patients.
In NK cells, NKG2D serves as a primary activation receptor, which by itself triggers cytotoxicity [50].
The found GSK-3β primary activation and reduction could also attribute to WNT signaling.
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It appears as if these compounds activate (indirectly via primary innate activation) Th1-mediated immunity, primarily via activation through TLR/CLR (dectin) signalling.
Figure 6 shows a hypothetical model of how phagocytosis might lead to a primary neutrophil activation, followed by secondary monocyte/macrophage activation.
These genes illustrated a distinct immune response, resembling a wound healing process, including a primary neutrophil activation and a secondary macrophage activation, a local acute-phase response (APR) and a late B lymphocyte response without any signs of infection.
Patients on haemodialysis are at increased risk of developing active tuberculosis after primary infection, activation of quiescent disease or reactivation of pre-existing tuberculosis infection [46].
DUSP26 (MKP-8, LDP-4) was originally described as a dual specifity phosphatase with enzymatic activity against p38 MAP kinase resulting in dephosphorlyation of the primary p38 activation sites, Thr180/Tyr182.
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