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Substitution of single amino acids in the protease primarily resulted in reduced affinity through increased koff for the inhibitors.
The manganese nitrate (MN) precursor primarily resulted in large particles on the silica support, while the manganese acetate (MA) precursor mainly resulted in a highly dispersed manganese oxide on the silica support.
Due to inhibition of NF-κB activation, deficiencies in any of these molecules primarily resulted in reduced IL-2 production by conventional T cells.
The addition of the short reads from spore 4 primarily resulted in many more short contigs.
Loss of ash2 primarily resulted in increased sense transcription, and loss of shg1, spp1, or swd3 predominantly affected intergenic transcripts.
An initial spate of clinical trials attempting the treatment of haemophilia with gene transfer primarily resulted in the demonstration of good safety profiles, but without efficacy.
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Infectious spread from the frontal sinus to the anterior cranial fossa primarily results in subdural and epidural empyema.
As a result, it is believed that histone acetylation primarily results in a more "open" chromatin configuration, serving as a "mark" of active gene transcription.
While electrical injuries primarily result in burns, they may also cause fractures or dislocations secondary to blunt force trauma or muscle contractions.
Phage display with HIV-positive sera primarily results in the identification of immunodominant regions, such as KLIC, because of the abundance of antibodies targeting this region [41].
Under such stimulation, acute ATP depletion would primarily result in the inactivation of Na-K+ pumps, because such Na+/K+-ATPases are the most energy-consuming pathway in neurons [30]; this in turn causes the disruption of intracellular ion homeostasis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com