p27Kip1 is a key cell-cycle regulator whose level is primarily regulated by the ubiquitin proteasome degradation pathway.
PAF levels are primarily regulated by PAF acetylhydrolases (PAF-AHs).
Nrf2 is primarily regulated by Keap1, a substrate adaptor for a Cul3-containing E3 ubiquitin ligase.
The levels of gene expression are primarily regulated by their position on the genome.
During metII arrest separase appears primarily regulated by securin binding, not CDK1/cyclin B1.
"Therapists are primarily regulated by state licensing boards," Ames told VICE News.
Unlike tobacco, where the marketing is overseen by the FDA, alcohol advertising in the U.S. is primarily regulated by the alcohol companies themselves.
SREBP expression is primarily regulated by cellular cholesterol [36].
In skeletal muscle cells, glucose utilization is primarily regulated by glucose uptake.
Fatty acid β-oxidation is primarily regulated by the import of fatty acids into mitochondria.
Similarly, HSL activity in adipose tissue is primarily regulated by post-translational mechanisms [49].
