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In contrast, in the six patients with more than one pretreatment (two patients after two chemotherapies, four patients after chemotherapy and chemoradiotherapy), five patients primarily progressed during treatment with irinotecan plus docetaxel and only one patient achieved disease stabilisation, which was of short duration (16 weeks).
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For example, although the epidermal flanks have a similarly straightened, parallel geometry as they near the dorsal midline in both Oncopeltus and Tribolium (e.g. Fig. 1G), Tribolium closure is scalloped while Oncopeltus zippering is more akin to that in Drosophila, primarily progressing from the posterior canthus (Panfilio and Roth, 2010).
In recent years, NMT has progressed rapidly primarily due to advancements in brain-imaging technologies, which have revealed the brain's plasticity (its ability to change) and also the different networks in the brain that music can activate.
Diabetes is a disease that progresses primarily with physical and psychological problems and impairs the associated quality of life significantly.
The recent rise in the discovery rate of non-5q clinical and genetic entities is primarily due to progress in next generation sequencing technology development (Fig. 4).
Applying this assay to RNCs of varying length revealed that in the absence of CT8, Cys49 progressed from a primarily NEM-accessible environment to one that was inaccessible.
In recent years PET has progressed from being primarily a research tool to being a clinical imaging technique which adds to and complements existing anatomical and functional modalities.
This review primarily focuses on those approaches that have progressed to clinical evaluation or implementation.
These workers studied groups of animals with experimentally-induced FMD and measured temperatures (primarily around the coronary band) as disease progressed.
Participants primarily looked at room cues during the early segment of each trial, but primarily focused on the apparatus as the trial progressed, suggesting distinct, sequential stimulus functions.
The advent of internet wagering, including the likes of Advanced Deposit Wagering (ADW), has slashed funding for horsemen and purses, the revenue for which is primarily funded from on-track handles that traditionally progressed towards a 50-50 model between the two.
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