Our results appear to primarily implicate three COGs, none of which, however, is directly responsible for enzymatic transformation of ethanolamine.
As we excluded subjects with pre-existing peripheral artery occlusive disease (PAOD) from our study, and the time courses of SSc patients differ substantially from those of patients with PAOD during ischemia, our results primarily implicate small vessel disease as the origin of the detected BOLD signal alterations in skeletal muscle.
Whereas studies that show that NF-(B promotes aging primarily implicate either p65 or NF-(B in general, the current work is related specifically to Nfkb1.
Comparatively, CD16+ monocytes are primarily implicated in human atherosclerosis.
While the Self-Incrimination Clause primarily implicates the law of criminal investigations, the Clause also protects against self-incrimination that may occur at trial.
Primarily implicated in immune responses, NF-κB has been also shown to negatively regulate skeletal muscle differentiation [13], [14], [15].
As reviewed elsewhere [33], [34], prenatal PolyI C treatment in rodents induces a variety of behavioral, cognitive and pharmacological dysfunctions primarily implicated in schizophrenia and autism.
In younger people without genetic/developmental abnormalities, mechanical factors due to trauma are primarily implicated in the initiation and progression of OA lesions [12].
In the context of object recognition, it has been suggested that the dorsal visual stream is primarily implicated in attending to objects in near space, whereas the ventral visual stream is primarily implicated in attending to objects in far space [2], [7], [8], which fits quite well with the dual visual system hypothesis [9].
Findings have primarily implicated CNS-specific CD4 T cells in the pathology of experimental autoimmune encephalomyelitis (EAE), where myelin-specific T cells penetrate the CNS and promote axon demyelination there [5], [6], [7], [8], [9].
These findings, together with the lack of correlation noted between VEGFR-2 and the microvascular density in these tumors reinforce the idea that the role exerted by VEGF/VEGFR-2 in melanoma is primarily implicated in promoting melanoma cell growth and may be independent of the development of a tumor related capillary network [21], [22].
