Different references generated different enrichment p-value but produced the similar result that the entire subnetwork primarily functions for development, with corrected p-value < 6.517e-62 (Bonferroni correction using entire annotation, referred as corr, hereafter) (Additional file 1: Figure S1A).
Engrailed proteins primarily function as transcriptional repressors through an interaction with the co-repressor protein groucho9, although they have also been shown to regulate translation through binding to the eukaryotic translation initiation factor 4E10.
(I6/1; female) In this section we have shown that the teachers interviewed employed a variety of emotion-regulation strategies that primarily functioned to help them cope with negative emotional experiences.
ERK1/2 primarily functions in cell proliferation in comparison with its role in apoptosis, while activation of JNK and p38 MAPKs is generally associated with promotion of apoptosis.
Using contextual information from conserved gene neighborhoods we show that these proteins primarily function in restriction-modification systems, in conjunction with diverse superfamily II DNA helicases and endonucleases.
The low EE/IE score, however, suggests that Hrp1 primarily functions early in mRNP biogenesis, consistent with prolonged cytoplasmic binding of Hrp1 denoting an aberrant mRNP.
On 17 March 2003, only 17 of the 66 secondary schools in New Caledonia were functioning, with others still closed primarily due to safety concerns.
MyD88 primarily functions because its TIR domain heterodimerizes with the receptor and homodimerizes with another MyD88 molecule to recruit downstream signaling molecules.
Miller and Cohen's (2001) guided activation model proposes a cognitive control system with very similar functions and identifies these functions primarily with the prefrontal cortex.
Kindergarten teachers are qualified to work with children and primarily function as role models for children and their parents because of their pedagogical skills [ 15, 16].
MR function in the kidney has been studied extensively focusing on its roles in controlling blood pressure and salt and water balance, functions primarily associated with the renal tubule not glomerulus.
