Sentence examples for primarily eliminates from inspiring English sources

The underlying cause of the association between MSH2 mutation and cancer is thought to be a failure of MMR, a pathway which primarily eliminates base base mismatches and insertion/deletion loops arising during DNA replication.

DTG is primarily eliminated through metabolism, and renal elimination of unchanged drug represents less than 1%% of the total dose administered.

Volasertib is primarily eliminated unchanged with metabolism representing a relatively minor elimination route as indicated by low exposures of the main metabolite (data not shown).

Metformin is primarily eliminated via the renal route through tubular secretion, with a plasma elimination half-life of 6.2 hours.

As VS is primarily eliminated through the liver into the bile and feces, patients with obstructive liver disease are more susceptible to its toxic effects, requiring a dose reduction depending upon the serum bilirubin concentration.

Methylnaltrexone is primarily eliminated as an unchanged drug (85% of the administered dose).

In dogs, topiramate is not extensively metabolized and is primarily eliminated unchanged in the urine.

Autoreactive T cells are primarily eliminated in the thymus by negative selection (central tolerance).

Linagliptin is primarily eliminated unchanged via the feces, by which 84.7% of an oral dose is eliminated.

Edoxaban is primarily eliminated unchanged through multiple pathways, with approximately 50%% of systemically absorbed drug eliminated via renal excretion.

Naltrexone is primarily eliminated by the liver with only 1% of an oral naltrexone dose excreted in urine [ 28].