Sentence examples for primarily adverse from inspiring English sources

Apart from the primarily adverse effect of problematic alcohol use on spousal mental health, differences in alcohol use between the spouses represents an additional risk factor, whereas spouse similarity may buffer negative effects of spousal alcohol consumption.

The key attributes responsible for this are the various limiting factors associated with conventional chemotherapeutics that primarily include adverse side-effects and development of chemoresistance.

Inhalation exposures to vanadium and vanadium compounds result primarily in adverse effects on the respiratory system.

Safety was assessed primarily by adverse events (AEs), including cardiac AEs; efficacy by complete response (CR: no emesis, no rescue).

Calculation of PNEC values should be based primarily on adverse effect end points that are directly relevant to protecting populations.

All agents carry a degree of risk, primarily in adverse effect profile, as well as benefit, based on effects on glycemic control and potential pleiotropic effects.

10 In many cases, poor adherence or discontinuation of therapy was thought to be an effect related primarily to adverse events or lack of therapeutic response.

Safety was assessed primarily by adverse events, but also by clinical laboratory evaluations, vital signs, physical examination findings, and electrocardiograms (ECGs).

The most common toxicities were primarily gastrointestinal adverse events (diarrhea [84%], nausea [45%], vomiting [37%]), which were primarily mild to moderate, typically transient, and first occurred early during treatment.

A more recent meta-analysis commissioned by NICE did not find a statistically significant difference among NSAIDs [ 82]; guidelines treat NSAIDs as a class differentiated primarily by adverse events [ 2, 3].

The results are consistent with the observation that increased adiposity and insulin resistance in European populations relate primarily to adverse physical health rather than mental health criteria of QoL (11, 12, 18).