At INESSS, the five factors defined by legislation that must be considered when preparing drug funding recommendations for the Minister of Health are: therapeutic value, reasonableness of price, cost effectiveness, the advisability of entering the drug on the list, and its impact on the health and social services system.
Another option for governments to consider would be sharing the risk with the manufacturer; on the basis of the uncertainty around the cost effectiveness a price reduction could be negotiated that remains valid until the data on efficacy become available.
No studies, other than the SHELf study that is currently being conducted in Melbourne, Australia, have examined the cost effectiveness of price discount interventions [ 18] and little is known about the impact of subsidies on the overall diet and possible unintended consequences on diet[ 14].
The influence of different drug prices on the cost effectiveness of TXA was explored in one way and probabilistic sensitivity analyses.
The objective of this study was to compare monthly costs (based on retail and wholesale prices) and the cost effectiveness of bilateral treatment with bimatoprost 0.03%, latanoprost 0.005%, and travoprost 0.004% for reduction of IOP in patients with glaucoma or ocular hypertension.
With an additional 0.18 QALYs/patient and an additional lifetime cost of £372/patient at price parity, the incremental cost effectiveness ratio (ICER) of UMEC/VI compared to tiotropium was £2088/QALY.
With these total production costs it should be possible to match a vaccine price that would provide cost effectiveness in a malaria endemic region, given a sufficient efficacy of the vaccine.
Analyses were undertaken to evaluate the price sensitivity of exenatide in terms of relative cost effectiveness.
We haven't yet mastered the technology or the price-effectiveness to offer fast vaccines to mutating viruses.
More generally, we show how LLIN programme cost effectiveness varies with bed net price, lifespan, usage and loss rates.
Orphan products are likely to have higher prices for modest effectiveness and their ICERs are expected to be higher than the cost effectiveness thresholds.
