Sentence examples for previously reported active from inspiring English sources
Herein we describe pharmacophore virtual screening based on previously reported active molecules that target the toxic RNA that causes myotonic dystrophy type 1 (DM1).
b Validation of the selected query; mapping of previously reported active compounds 4a and 4n [12] as well as 4a and 4f [13], showing RMSD values in acceptable range (0.2823-0.4993).
An X-ray crystal structure of the thiazolidinone hit in Leishmania major NMT showed the compound bound in the previously reported active site, utilising a novel binding mode.
Rather, despite its larger molecular mass relative to previously reported active-site hDAAO inhibitors [ 13, 22, 27, 30, 40], compound 2 displayed the kinetic properties of a canonical, active-site-bound hDAAO inhibitor.
It has been previously reported that active RhoA activity can down regulate p21WAF1 expression [ 25].
We analyzed the brain responses to BART only in active mode as no brain activation was observed in passive mode, as previously reported in active versus passive mode in BART paradigm sub-section (see Fig. 9).
These structural characteristics do not differ greatly from those of other previously reported piezoelectrically active vinylidene cyanide copolymers with vinyl acetate, vinyl benzoate, and vinyl pivalate or from those of piezoelectrically less active vinylidene cyanide copolymers with styrene and methyl methacrylate.
We have previously reported that active Notch signaling is essential in progenitor quiescence23.
At a heating temperature of 210 °C, α-Ni(OH 2, which is originally inside the precursor, serving as crystal nucleus could induce nickel formate to transform into α-Ni(OH 2 instead of previously reported highly active metallic Ni.
We previously reported engineering active ZFNs for six endogenous loci in Arabidopsis using the CoDA method (Sander et al. 2011).
Similar to the previously reported haze active protein BATI-CMe [ 11, 25], BATI-CMb and BATI-CMd belong to chloroform/methanol soluble (CM) proteins.
