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These previously published applications of RCR to experimental data have involved the analysis of diseased states.
This approach follows the practices of previously published applications of causal orientation methods by their inventors [ 16- 18].
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Here we describe in more depth the previously published application of the fluorescent probe 4,5-diaminofluorescein (DAF-2) in order to reliably measure low levels of nitric oxide (NO) as released from human endothelial cells in vitro.
Among several published applications of this technology, we have previously conducted comprehensive transcriptional analyses of the reference plant species Arabidopsis thaliana and rice [ 7, 9].
In contrast, previously published FAO application efficiencies for irrigation application methods (FAO, 1980) and ea values reported by the ICID/ILRI are substantially lower, representing a lower level of management and probably a less than optimal design.
A previously published dashboard application, the Toxcast Dashboard [99], also provides full access to single concentration assay data in the list of 'tested' assays endpoints if multi-concentration data are unavailable.
Oberhardt et al. [ 45] have very recently developed an elaborate process for reconciliation of genome-scale metabolic models, and demonstrated its application on the previously published models of P. aeruginosa PAO1 and P. putida KT2440.
This population forms the basis of the cancer dataset used to compare the previously published methods, and its characteristics are described in table 2. The process and results of the application of the four previously published methods of determining PCCRC rates is shown in figure 1.
Reviewer's report 2 – Prof. Marek Kimmel The model is an application of the previously published more general model of interaction of RNA polymerases, protein factors and secondary structure during transcription.
Previously published versions of the model have been revised.
The American College of Surgeons (ACS) has previously published tenets of surgical professionalism.
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