In addition, we have detected 3 pathogenic variations previously published in ours and other populations [ Abd et-aliz et al., 2008; Collin et al., 2008] (Table 2, Table 3, Figs. 3 and 4).
Compared to previously reported equations, ours are 7 69% more accurate.
Unlike the previously reported studies, ours uses an observational methodology, and two different regimens (not only the formulation) are compared.
In our review of seven cases (six previously reported cases plus ours) of intestinal metastasis from angiosarcoma, the prognosis of patients with peritonitis was remarkably poorer than that of patients with hemorrhage alone.
These results were consistent with the previously published data, including ours [ 5, 12, 20].
From the functional point of view, four previously published papers, including ours, have shown that RETN promoter activity with G of rs1862513 is higher than that with C (see Table 1 for summary) [ 2– 5].
This supportive regimen, established in previously published studies of ours (Koukourakis et al, 1998b, 2001), effectively protected from neutropenia patients receiving concurrent chemo radiotherapy using a high dose of carboplatin fractionated regimen or docetaxel/carboplatin chemotherapy.
Several groups, including ours, have previously shown that colon tumours that acquire resistance to the anti-EGFR drugs cetuximab or gefitinib exhibit an activation of alternative downstream signal transduction pathways, including increased activity and/or overexpression of pMAPK and VEGF (Viloria-Petit et al, 2001; Ciardiello et al, 2004; Morgillo and Lee, 2005).
Unlike previously studied global measures, ours avoids standard equilibrium considerations and the well-known problems of Boltzmann Brains and the youngness paradox.
The difference among previously published studies and ours may be due to a more conservative permutation based significance cutoff in our Rqtl analysis.
