Therefore, whereas production of R-bodies is necessary for killing by C. taeniospiralis, as described previously, it is not sufficient for killing by recombinant Escherichia coli.
The use of a prophylactic regimen of dexamethasone, ranitidine, and chlorphenamine, previously described, was not sufficient to prevent hypersensitivity reactions in two patients at 120 mg m−2, therefore a more stringent prophylactic regimen (Kwon et al, 2002) might be necessary.
The map resolution of most previously reported QTL are not sufficient for determining precise locations of QTL.
An electric hammer used previously for building blocks was not sufficient for adequate compaction of paving blocks.
Wishes expressed previously by the patient are not sufficient, as the subsequent experience of a serious illness can profoundly modify the patient's value system, leading to a change in the way he or she envisions the end of life.
Dual-positivity for these markers has been suggested previously as a necessary, but not sufficient, criterion to identify EPCs [ 19].
The NES-A region was shown previously to be important but not sufficient for the protein-protein interaction known to occur between Upf2p and Upf3p (7, 25).
Indeed, we have previously demonstrated that Rab25 is not sufficient to transform immortalized but non-tumourigenic cells (Cheng et al, 2004) and similarly, Rab25-knockout mice do not exhibit significant anatomical and pathological abnormalities (Nam et al, 2010).
We believe that our data show that at least some of the previously considered technical artifacts are not sufficient to explain this difference, suggesting that both distant cis regulation and strong trans regulation play a bigger role in gene expression than previously appreciated.
However, the sensitivity of the previously identified serum biomarkers was not sufficient for diagnosis of gastric adenocarcinoma because the sensitivity of tumour markers such as carcinoembryonic antigen, cancer antigen19-9, and CA72-4 was low (20 30%) (Kodama et al, 1995; Reiter et al, 1997; Marrelli et al, 1999, 2001; Gaspar et al, 2001; Ishigami et al, 2001).
