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Previously, modifications of the oncolytic adenoviral fibers have focused on retargeting viruses through incorporating receptor-specific ligand peptides into the viral fibers, or altering viral tropism through the replacement of the fiber knob alone or together with the shaft domain to form chimeric fibers.
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As mentioned previously, modification of siRNAs would affect their loading efficiency into RISCs, which is another factor that could affect K2.
In this paper, all previously proposed modifications of natural gamma ray log and its spectral components data were reviewed and a new calibration equation for reliable assessment of the clay content in the Shurijeh reservoir Formation was presented.
For the clay content estimation purpose, the application of the empirical relationship was found more reliable than the previously proposed modifications of the natural gamma ray log, due to its indicator values and low estimation errors.
Based on the available genetic data, catalytic site configuration and contextual information we predict that these proteins catalyze previously uncharacterized modifications of surface proteins in various biological roles.
Using mass spectrometry analysis, we firstly confirmed acetylation as a previously unreported modification of TFEB and found that SIRT1 directly interacted with and deacetylated TFEB at lysine residue 116.
Another, previously unappreciated modification of DNA, hydroxymethylation, has become a subject of considerable attention.
Mice were bled at 4 weeks after immunization and sera were analyzed for antibodies reactive with native murine CII using a previously described modification of an ELISA [ 3].
To define the metabolic syndrome among the young participants aged between 12 and 17 years, we used a previously proposed modification of the definition proposed in the National Cholesterol Education Program Adult Treatment Panel III.
If, however, we wish to capture the transient activation of ERK, we can do so using a previously unpublished modification of the Boolean steady-state method which is available in CellNOptR.
These previously unsuspected massive modifications of Earth's past environments are, of necessity, reflected in the evolutionary history of life.
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