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In human gliomas most of the genetic alterations that have been previously identified result in abnormal activation of cell growth signaling pathways and deregulation of cell cycle, features recapitulated in our model by oncogenic Ras expression and retinoblastoma (Rb) inactivation respectively.
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The possible involvement of SCARB2 and the previously identified results at GBA seem to implicate the lysosome in the etiology of this prevalent disorder.
Gene duplicates that were previously identified as resulting from the WGD event are henceforth referred to as 'ohnologs' and were analysed separately from those resulting from SSD events to test if these two pools of duplicated genes behaved differently with respect to their rates of molecular evolution.
The previously identified A496S mutation results from a change from a guanine to a thymine (Davies et al, 2005).
Linkage analysis suggests that tgr2 and tgr3 do not correspond to a mutation at previously identified maize loci resulting from other forward genetic screens, while tgr1 shows linkage to a characterized gene.
Since all the patients were part of previously identified clusters, tMRCA results were compared between the Bayesian analysis of the complete set of 307 sequences and separate analyses based on cluster sequences.
Unfortunately, the variant of eye gaze previously identified in the results was not anticipated and was only noted once data collection began; so formal measurement of eye gaze was not performed in all subjects.
This demonstrates that some of the immune abnormalities previously identified in DBA/2J mice result from intrinsic defects in APCs.
Morphological variation previously identified among wolf populations resulted in recognition of multiple subspecies of wolves in the Pacific Northwest.
However, previously identified O-alkenyl ions resulting from the O-alk-1'-enyl chain of pPtdEtn [25] were either present at very low intensities or could not be detected under the experimental conditions employed that were largely dependent on the abundance of the corresponding molecular ions.
These results (previously identified for mESCs [ 15, 16]) outwardly contradict our understanding of transcriptional regulation, in which TFs and HMs play complementary yet distinct roles in RNAP-II recruitment and elongation.
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