Suggestions(1)
Exact(4)
Similarly while the previous trial reported migraine associated variants, in the MTHFR and MTRR genes to have a significant effect on migraine treatment response, the current trial did not observe any significant effect of the MTHFR C677T gene variant on migraine treatment response.
The previous trial reported a 67% risk reduction [ 21].
Although it is difficult to compare the incidence of neutropaenia, we observed no incidence of febrile neutropaenia, whereas the previous trial reported febrile neutropaenia in three patients (7%).
A previous trial reported that a supervised exercise regimen was superior to placebo, so we found it difficult to justify the inclusion of a placebo group.
Similar(56)
In addition, two previous trials reported positive outcomes of switching to quetiapine XR from other antipsychotics in patients with suboptimal prior pharmacological treatment [ 35, 36].
Previous trials reported EPA increases of 200 to 900% over a period of 3 to 8 weeks to be associated with beneficial effects on nutritional parameters [ 46, 47].
It remains possible that the infants did not receive a dose of L reuteri large enough to establish an effect; however, the trial's probiotic dosing was the same as that of three previous trials reported as effective.
The QPS is not being used prior to the consultation, while, in previous trials reported in literature, 8– 16 patients take the QPS into the consultation to serve as a reminder to ask questions.
There were little data regarding the FNR for SLN, previous trials reported a FNR of 11.3% for use of Technetium-99 m [ 20] and 10.0%-17.9%for the blue dye technique [ 12, 13, 15, 16].
Higher intake of fish or n-3FA supplements is associated with lower rates of coronary heart disease and death (9, 10) and lower atherosclerotic burden (11, 12), and some, but not all, previous trials reported reduced CV events in patients receiving n-3FA supplements (13– 13).
A previous controlled trial reported that DIM relieved recurrent breast pain (cyclical mastalgia) (Zeligs et al, 2005).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com