Based on the considerable number of patients in our cohort whose disease was differently staged by the sixth or the seventh editions of TNM classification, previous studies using the sixth edition for staging should reconsider the changes of the seventh edition prior to comparison with new data emerging from treatment of patients with perihilar cholangiocarcinoma.
14 In a previous study using the model, flexion of the second bending portion was more effective for insertion of the endoscope into the lower bile duct when combined with flexion of the first bending portion of the endoscope.
First, previous studies using the CAT mixture model showed that it handles the substitutional saturation of the data better than classical homogeneous models [ 31], hence alleviating phylogenetic artefacts [ 33]; and second, because in contrast to other mixture models [ 32], it does not specify the number of mixture components a priori.
Third, the outcome in the control arm is similar to previous studies using the Mayo Clinic regimen (Haller et al, 1998).
In a previous study using data from the first two rounds of the survey in Manicaland, all types of orphans were less likely to have completed primary school than their unaffected counterparts (Nyamukapa & Gregson, 2005).
The absence of TRAbs in HT with the ELiA™-TSH-R assay was also surprising, since previous studies using second and third generation assays detected TRAbs in 5 20% of HT patients [14, 24, 25, 26], putatively B-TRAbs or neutral TRAbs.
One previous study used second-order partial correlations of genetic associations to elucidate genetically determined relations between metabolites [ 17].
The toxicities experienced by the patients are presented in Table 4.> MVAC elicited a significant response rate in GP-failed patients with advanced urothelial cancer in the current study, which is consistent with the results reported in previous studies using MVAC in the second-line setting.
Second, the previous study used matching to compare subjects with and without OAB; as such, their study design limited the accurate determination of prevalence of OAB symptom severity and estimation of PAF.
First, our previous study used a statistic (hierarchical FST) detecting differences between continental groups that should have emerged recently, whereas our 2DNS statistics are more sensitive to older events.
