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Another explanation could be age: the mean age was >50 years for only three of the seven pain classes in the previous study (regional lower musculoskeletal pain, widespread musculoskeletal pain and widespread whole body pain).
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In a previous study, using regional MRI, we found that morphological alterations throughout the brain in the YAC tg152F7 were not uniform: the total brain volume was 14% greater in transgenic mice than in wild-type mice, with an effect 2,5 greater (25% /10% in the ventral region (including the thalamic-hypothalamic region) than in the cortex (10% greater volume) [23].
Most of previous studies on regional poverty evaluations are based on statistics collected typically in administrative units.
However, in previous studies, such regional disparities are often overlooked, hence this study analyzes 6 Korean sub-national and 31 Chinese provincial levels while taking into consideration of reginal disparities.
It has been reported in several previous studies that regional block, opioids, and nonsteroidal antiflamatory drugs could decrease the incidence of EA [ 19– 22].
The samples used in the present study have been examined in our previous studies of regional homogeneity [ 13], amygdalar connectivity [ 12, 28], thalamic connectivity [ 14], and marginal division connectivity [ 29] during resting states.
Previous studies of regional problems in primary care which have used general practice consultation databases have been limited by either concentrating on a subset of codes (generally from within the Musculoskeletal Disorders Chapter), had small samples, have scrutinised written records, or restricted analysis to specific sites or ages[ 9, 15- 19].
The differentiation estimates between populations (ΦPT = 0.286 in the dwarf males and 0.374 in the female shoots) were comparable to previous studies of regional diversity in mosses where FST (or comparable differentiation measures) averaged 0.213 for commonly sexual taxa and 0.314 for mainly clonal taxa (review of 30 terrestrial moss species, 25 of which were unisexual and five bisexual) [ 69].
In accordance with the previous study a significant regional variability of extreme rainfall characteristics is observed, which can partly be explained by the mean annual precipitation patterns and a sub-regional division of the country in a western and eastern part.
A previous study indicated that regional volumes are positively correlated to their mutual information, which measures the functional connectivity between the region and the remaining brain regions [84].
While our present data show significant up-regulation of pebp in a single temperate population under DI conditions, the previous study suggested a regional effect on pebp expression in these populations, rather than a simple over-expression of pebp under DI conditions.
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