Sentence examples for previous fate from inspiring English sources

Although previous fate mapping experiments have identified the majority of derivatives of neural crest cells and cranial mesoderm in the jaw, the spatial relationships and the interactions over time between both cell types are not completely understood.

Furthermore, our previous fate mapping experiments indicated that in wild-type (WT) mice CD8αα IEL with TCRαβ are derived from precursors expressing RORγt, which is an isoform of an orphan nuclear receptor, RORγ, encoded by the Rorc gene [6].

Previous fate maps of the chick wing using DiI labelling to trace cell lineages showed that all three digits come from cells in the posterior part of the early wing bud tip and that this region expands across the antero-posterior axis as the bud grows out [33], [6].

This conclusion is in contrast to our previous fate mapping studies using a BAC transgenic Ascl1::CreER™ mouse, where essentially all lineage marked cells differentiated to mature neurons within 30 days in the SVZ and the SGZ, which suggested that in this paradigm Ascl1 lineage cells are restricted to the transit amplifying populations [7].

This allowed us to statistically evaluate the accuracy of the estimated spatio-temporal pattern of deformation dynamics, which is an advantage of our study over previous fate mapping studies and lineage analyses.

Studies of stringently defined models of mouse reprogramming have shown that cell-type-of-origin-specific differences in gene expression and differentiation potential exist in early passage iPSCs, leading to the hypothesis that an epigenetic memory of previous fate persists in these cells [ 98, 99].

These glial promoters were selected since previous fate-mapping studies of glial lineages demonstrated PLP- as well as GFAP-promoter activity in progenitor cells during fetal development of the brain.

Previous fate-mapping studies have shown that Cre-dependent recombination driven by GFAP or PLP promoters during embryonic development labels distinct glial and neuronal cell populations [2] [4], [18].

Previous fate-mapping using a Neurod6 (NEX) driven Cre mouse line has shown IPC contribution towards the formation of upper layers (Wu et al. 2005).

Previous fate-maps have demonstrated that at embryonic day (E) 2 (stage [st.]10), r1 is defined by the boundaries of the expression domains of, rostrally, Otx2 [ 17] and, caudally, Hoxa2 [ 2].

In accordance with results from previous fate-mapping studies using Wnt1-Cre and chromogen reporter mice (Chai et al., 2000; Jiang et al., 2000; Jinno et al., 2010; Kameda et al., 2007), mG labeling elicited by the Cre driver was limited to cells of established neural crest origin (Fig. S1A- C).