Exact(17)
Apart from previous exacerbation history, we currently have no good tools to identify frequent exacerbators.
During baseline registration, 88 patients (25.9%) reported an exacerbation the year before baseline (previous exacerbation).
This might have led to an overestimation of previous exacerbation as predictor of such prescribing.
Previous exacerbation was a strong predictor of ICS/LABA prescribing only in patients with severe COPD.
Records within 28 days of a previous exacerbation record were considered to refer to the same episode.
The interval between COPD exacerbations is defined as the days between the previous exacerbation event and the next event.
Similar(43)
The study confirms that previous exacerbations strongly predict future exacerbations in patients with COPD or asthma.
Patients answered an epidemiological questionnaire that covered smoking habits, respiratory symptoms, previous exacerbations and treatments.
Reasons are speculative, but may include treatment of dry cough, previous exacerbations or difficulty in tapering off therapy.
Though exacerbations tend to become more frequent in those with poor lung function, it has recently been shown that the single best predictor of exacerbations is a history of previous exacerbations [ 4].
Predictive factors in the model were age, gender, previous exacerbations, influenza and 23-valent pneumococcal immunisations, number of previous visits to the General Practice and severity (GOLD), with an area under the ROC curve (AUROC) of 0.70.
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