Sentence examples for prevents the sequestration of from inspiring English sources

We propose that HbF and PfEMP-1-specific IgG substantially attenuate parasite virulence by weakening cytoadherence in vivo, which prevents the sequestration of most parasitized RBCs at the late ring stage (only early ring forms are observed circulating in the bloodstream) and thus enables their removal from the bloodstream by the spleen.

In this way, SMAC/DIABLO prevents the sequestration of caspases, facilitating the apoptotic pathway.

Our data suggest that overgrown spindles could result from the activity of factors that trigger a persistent microtubule formation in the spindle area, because the absence of functional Imp-α2/Imp-β complexes prevents the sequestration of SAFs and further hampers other factors to foster mitotic progression.

It was suggested that levamisole prevented the sequestration of these parasites as they matured from ring stages following treatment.

In the alternative interpretation, they are viewed as passively promoting normal DNA methylation by preventing the sequestration of DNMTs [ 107, 117] at unresolved non-B structures [ 10].

A key implication of the hypothesis is that helicases, like the lymphoid-specific helicase and alpha thalassemia/mental retardation syndrome X-linked helicase, passively promote accurate maintenance of DNA methylation by preventing the sequestration of DNMTs at sites of unrepaired non-B DNA structure.

Concerning inflammation, it has been shown that BN/GRP-like peptides ameliorate burn-induced intestinal inflammation by preventing the sequestration of neutrophils in the injured tissue [ 81] and that these peptides presumably are mediators of inflammatory reactions during pulmonary inflammation [ 82].

Induction of apoptosis by c-MYC overexpression is attributable in part to activation of the p19ARF– pathwayhway, in which p19ARF upregulation prevents the degradation of p53 by sequestration of the ubiquitin ligase MDM2.

The inhibition of translation in suspension may be due to the fact that phosphorylation of eIF2α at Ser51 results in the sequestration of its GEF, eIF2B preventing eIF2α-GTP hydrolysis [12].

It also provides strong evidence that oligomers are the key inducers of synaptic dysfunction and that the sequestration of these cytotoxic species can effectively prevent their damaging effects.

These data suggest that the sequestration of galectin-7 into the nucleus would prevent this protein from interfering with tumor progression or regression, leading to treatment resistance.