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The C>T SNP in the FLT1 promoter changes a critical mismatch in a p53 ½ site that prevents function into a consensus sequence that provides for weak p53 transactivation [17].
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Next, we investigated whether adenosine receptors have a crucial role in preventing function of adenosine.
Therefore, it seems likely that the additional amino acids derived from a usually noncoding genomic region cause structural changes that prevent function of the mutant protein.
Moreover, in adenosine receptors knockout mice, 5′-AMP treatment also increased survival rate in GalN/LPS-induced ALF, displaying similar preventing function to WT mice (Supplementary Figure 1).
Second, freedom of expression is the flimsy catch preventing functioning societies from sliding into autocratic tyranny.
Thus, targeting CRABP2 function prevents RARα function and affects, in a negative and irreversible fashion, the transcriptional status of RA-responsive genes downstream of RARα.
Add a debounce function to prevent another function from firing more frequently than you specify.
Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion.
Although necessary for bone healing, immobilisation temporarily prevents hand function and may necessitate corrective physiotherapy later.
Minimal defect density on a wafer is a must, as a single shortcut prevents the function of the sensor chip.
Rasl11b inhibitory action was only observed in oep-deficient backgrounds, suggesting that normal oep expression prevents Rasl11b function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com