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When combined with reported P-value for a peptide hit using a score distribution model, this new measure prevents exaggerated statistics.
The P-value obtained through (23) prevents exaggerated statistics in peptide identification, and thus may reduce protein misidentification for identification methods founded on peptide identification.
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In mice with conditional Bmpr2 deletion in ECs, low-dose FK506 prevented exaggerated chronic hypoxic PAH associated with induction of EC targets of BMP signaling, such as apelin.
Changing only a small volume of water at a time was therefore found to prevent exaggerated aggressive interactions among P. scalare specimens and to reduce the probability of injuries, stress, and detrimental impacts on fish welfare.
HBZ might thus prevent exaggerated TAX expression and allow infected cells to evade an immune response.
Upon LPS challenge, the levels of phospho-JNK rose further, whereas TUDCA treatment prevented exaggerated JNK activation.
As an example of how this formulation may prevent exaggerated statistics, let us consider the case where P h = 10-50 and P M = 10-8.
This communication should enable the public to achieve realistic risk perception, give clear information on how people can minimize their infection risk, and prevent exaggerated reactions and anxiety.
Given concomitant release of various alarmins from damaged cardiomyocytes (Zhang et al, 2012), it is tempting to speculate that S100A1 liberation might mitigate actions of pro-fibrotic alarmins, thereby preventing exaggerated post-MI fibrosis.
TLR activation must be tightly regulated to prevent an exaggerated immune response from devastating the host.
T-effector cell production of IL-10 has been considered as a self-limiting mechanism to prevent an exaggerated T-cell response in the intestines as well as in other autoimmune diseases, which otherwise would be detrimental20.
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CEO of Professional Science Editing for Scientists @ prosciediting.com