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With medicine's increasing success, he said, "anything is permitted if it saves life, cures diseases, prevents death".
(The data have never been strong enough to warrant conclusions about whether it prevents death).
Efficacy has also been shown retrospectively, as patients frequently experience an exacerbation of their asthma upon withdrawal of ICSs, whilst the regular use of low dose ICSs prevents death from asthma.
We show here that minocycline delays neurodegeneration in ts1-infected mice, and that it prevents death of cultured astrocytes infected by ts1 through attenuating oxidative stress, inflammation and apoptosis.
A spokesman for Bristol-Myers Squibb pointed out that IVUS results are not the same thing as showing that a drug prevents death, and said the company stands by the safety and efficacy of Pravachol, its top seller.
In addition, minocycline prevents death of primary neurons when they are cocultured with ts1-infected astrocytes, through mechanisms involving both inhibition of oxidative stress and upregulation of the transcription factor NF-E2-related factor 2 (Nrf2), which controls cellular antioxidant defenses.
Similar(36)
"There's no high-quality evidence," he said, "that shows that skin cancer screening prevents deaths".
Similarly, renal replacement therapy with dialysis prevents deaths related to toxicant-induced acute renal failure.
The exact working mechanism by which dexamethasone prevents deaths in bacterial meningitis remains unknown [ 14].
The good news is that prevention of one appears to prevent death from the other.
There was bittersweet poetry in the timing: death preceding life and preventing death.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com