Most of them are subunit vaccines; in general, they can be divided into two groups, namely, the vaccines for primary prevention (intended to replace BCG) and booster vaccines (used for revaccination).
I once heard him say, in a college lecture on cancer prevention, "The goal is to replace fear with understanding.
The majority of tertiary prevention interventions are not designed to replace pharmacological therapy, but rather to complement it.
When referring to the effects of PEEP, it is true that it would have been more appropriate to replace recruitment with prevention of derecruitment as we did in a recent paper measuring the effect of PEEP on lung aeration [ 7].
Idrabiotaparinux, a reversible long-acting pentasaccharide, and new oral anticoagulants, such as dabigatran etexilate, rivaroxaban and apixaban, have been designed to replace warfarin for extended prevention or treatment of VTE.
All these findings together highlight the WHO 2004 malaria prevention program failure and suggest the need to replace SP. However is it worth replacing SP when the WHO goal of four ANC visits [ 3] during pregnancy is not yet achieved?
The proposal to replace antisocial behaviour orders with crime prevention injunctions, which will carry effective sanctions if breached, could work.
However, when using these results to generate a hypothesis, it still seems reasonable to replace SFA by PUFA in the secondary prevention of CHD, although SFA should not be completely substituted by n 6 fatty acids as recommended by the FAO.
In the absence of an effective drug to replace SP for IPTp alternative strategies for the prevention of malaria in pregnancy need to be evaluated.
As tissue engineering strategies to replace missing or damaged tissue advance, the focus on prevention and treatment of concomitant infection has also begun to emerge as an important area of research.
Examples include co-prescribing antibiotics and lactobacillus acidophilus to replace the intestinal bacteria destroyed by antibiotics, and using milk thistle (Silybum marianum) for the prevention of liver dysfunction in clients undergoing anticancer treatment [ 48].
